If you see an error when trying to implement changes with an optimization, it might be because the campaign in which the changes are being applied is a Google Ads Express campaign. 

Google Ads doesn't allow changes to be made to these campaigns through the API.

If you get the following error when trying to apply changes in any optimization, it might be because the MCC has read-only access to the Google Ads account in Google Ads. 

Google Ads accounts can have different access levels, so this might be the reason why Optmyzr can't make any changes. 

You can check the access level of that MCC email directly in Google Ads. 

If you get the following error when trying to apply changes in any optimization, it might be because you are trying to make changes in a Youtube campaign.

Google Ads doesn't allow us to make changes to Youtube campaigns through the API.